The worst sweeteners are artificial sweeteners, such as sucralose, saccharin and aspartame. These are the worst sugar substitutes because these sweeteners are made in a laboratory, meaning they are not found in nature. Some research on the daily and long-term use of artificial sweeteners suggests a link with an increased risk of stroke, heart disease and death in general. However, other things people do, or healthy habits that people don't adopt, may be the cause of the increased risk.
Aspartame — (Equal, NutraSweet, NatraTaste Blue). This post is about artificial sweeteners, also known as calorie-free sweeteners or non-nutritive sweeteners, and explains why you should look for healthier alternatives to them. In general, artificial sweeteners are safe in limited quantities for healthy people, including pregnant women.